PLAB 1

What PLAB 1 covers

Questions follow the MLA content map, at the level of a doctor starting Foundation Year 2.

BlueprintMLA content map, September 2026
LevelStart of Foundation Year 2
Results areas10
Area weightsNot published

The ten areas in your results

Area of clinical practice
Cardiorespiratory
Gastrointestinal
Endocrine, metabolic and clinical haematology
Child and adolescent health
Mental health
Musculoskeletal
Neurosciences and senses (including skin)
Renal and urology
Reproductive health
Ethics and other

What is in and out

  • In: common, important or acute conditions an F2 doctor sees, including those common in emergency departments.
  • In: managing long-term conditions seen in primary care, and ethics and professional practice.
  • Out: the advanced duties of a GP.
  • From September 2026 the map calls PCOS polyendocrine metabolic ovarian syndrome (PMOS).

Try 3 questions

Question 1MLA content map: Acute cholangitis
A 76-year-old woman has 2 days of right upper quadrant pain, rigors and yellow eyes. Temperature 38.9 C, pulse 112, blood pressure 108/70 mmHg. Bilirubin 86 micromol/L (under 21), ALP 410 U/L (30 to 130), white cell count 17 × 109/L. Ultrasound shows gallstones and a common bile duct of 11 mm. What is the most likely diagnosis?
Question 2MLA content map: Visual field defects
A 46-year-old woman has been bumping into door frames on both sides. Confrontation testing shows loss of the outer (temporal) half of the visual field in each eye. She has had irregular periods and milky nipple discharge for a year. Where is the lesion most likely to be?
Question 3MLA content map: Anaphylaxis
A 31-year-old woman develops hypotension, bronchospasm and a widespread rash minutes after induction of anaesthesia for elective surgery. She is treated with intramuscular adrenaline and fluids and the operation is abandoned. She is now stable in recovery, 30 minutes after the reaction began. Which blood test taken now best supports the diagnosis?

Next step

The GMC's MLA content map

Questions people ask

Is there a PLAB 1 syllabus?

Yes: the MLA content map. The GMC says it covers every topic and skill you need to pass.

Does the GMC publish sample questions?

Yes, 85 of them, published in December 2024.